2010 CityBeat Cincinnati Entertainment Awards for Theatre
- Local Actor in a Supporting Role in a Play, Michael Bath as Roy Cohn, Angels in America: Millennium Approaches & Perestroika
- Local Actor in a Leading Role in a Musical, Robert Pavlovich as Zero, Adding Machine: A Musical
- Local Actor in a Supporting Role in a Musical, Rich Roedersheimer as Shrdlu, Adding Machine: A Musical
- Ensemble Performance, Angels in America: Millennium Approaches & Perestroika
- Outstanding Play, Angels in America: Millennium Approaches & Perestroika

2009-2010 Cincinnati Enquirer Acclaim Awards
- Outstanding Direction in Independent Production, Jason Ballweber, Sideways Stories from Wayside School
- Outstanding Choreography in Independent Production, Lindsey Jones & Kim Popa, Sideways Stories from Wayside School
- Outstanding Non-Equity Ensemble, The Cast, Sideways Stories from Wayside School
- Outstanding Alternative Production 2010, Angels in America: Millennium Approaches
- Outstanding Direction, Brian Isaac Phillips, Angels in America: Millennium Approaches
- Oustanding Equity Supporting Performance, Michael Bath, Angels in America: MIllennium Approaches
- Outstanding Non-Equity Ensemble, The Cast, Angels in America: Millennium Approaches
- Most Valuable Player for the 2009-2010 Season, Liz Vosmeier, Know Theatre Resident Actress

2009 Cincinnati Magazine Best of the City Award
- "Best Bargains" - Know Theatre of Cincinnati

2009 Cincinnati CityBeat “Best Of Cincinnati”
- Best Theatre Value - Know Theatre of Cincinnati
- Best Transformation of Downtown - Cincinnati Fringe Festival

2009 CityBeat Cincinnati Entertainment Awards for Theatre
- Lighting, Sound, or Special Effects, Doug Borntrager & Sean Savoie, Eurydice
- Local Actor in Supporting Role in a Play, Robert Pavlovich, Eurydice

2008-2009 Cincinnati Enquirer Acclaim Awards
- Special Recognition, Doug Borntrager

2008 Cincinnati Magazine Best of the City Award
- "Discount Theater Tickets" - Know Theatre of Cincinnati

2007 Star Award from Over-the-Rhine Chamber of Commerce
- Arts Organization of the Year

2006-2007 Cincinnati Enquirer Acclaim Awards
- Supporting Performance, Molly Binder, See What I Wanna See
- Outstanding Direction, Jason Bruffy, See What I Wanna See
- Lead Performance, Liz Holt, See What I Wanna See
- Musical Direction, Alan Patrick Kenny, See What I Wanna See
- Lighting Design, Sean Savoie, See What I Wanna See
- Ensemble Performance, See What I Wanna See
- Outstanding Musical, See What I Wanna See
- Scenic Design, Samantha Reno, Last Sunday in June
- Outstanding Cabaret, Know Theatre of Cincinnati & New Stage Collective, Songs From An Unmade Bed

2005-2006 Cincinnati Enquirer Acclaim Awards
- Alternative Supporting Performance, Nick Rose, Last Days of Judas Iscariot

2006 Cincinnati CityBeat “Best Of Cincinnati”
- Best Hope for Inclusion

2005 Cincinnati Magazine Best of the City Award
- Best Fest “Cincinnati Fringe Festival”

2005 Cincinnati CityBeat “Best of Cincinnati”
- Staff Pick, Jay Kalagayan and Jason Bruffy

2005 Cincinnati Enquirer Acclaim Awards
- 4.48 Psychosis

2004 Cincinnati Enquirer
- Artistic Risk Taker, Artistic Director Jason Bruffy

2003 Cincinnati Entertainment Awards
- Best Ensemble, Corpus Christi
- Best Actor, Corpus Christi

2003 Post Corbett Awards
Extraordinary Events in the Arts, Corpus Christi